Nana Okogyedom Adoofi I has led impactful initiatives such as the Okogyedom Nation Building Foundation (ONBF), Okogyedom Development and Innovation Centre (ODIC), and Okogyedom Youth Empowerment and Education Development (OYEED). He is also a passionate advocate for public policies on sustainable entrepreneurship and the establishment of flexible and sustainable regulatory institutions.

A staunch advocate for sustainable entrepreneurship, Nana Okogyedom Adoofi I champions public policy reforms to create flexible and sustainable regulatory institutions for entrepreneurs. His work focuses on aligning economic growth strategies with regional integration and development goals.